Visceral leishmaniasis: rapid response to AmBisome treatment.
نویسندگان
چکیده
منابع مشابه
Visceral leishmaniasis: rapid response to AmBisome treatment.
There appears to be an increase in imported cases of visceral leishmaniasis in Northern Europe; many are children infected on holiday in the Mediterranean. Making the diagnosis in young children can be difficult especially when an adequate travel history is not obtained at presentation. Two infants with visceral leishmaniasis are presented who were initially felt to have alternative diagnoses a...
متن کاملShort-course treatment of visceral leishmaniasis with liposomal amphotericin B (AmBisome).
We evaluated liposomal amphotericin B (AmBisome; Vestar, San Dimas, CA) administered to 88 immunocompetent patients (56 children) with visceral leishmaniasis (VL) caused by Leishmania infantum. Thirteen patients received 4 mg/kg on days 1-5 and 10 (total dose, 24 mg/kg), and all were cured; 42 received 3 mg/kg on days 1-5 and 10 (18 mg/kg), and 41 were cured; 32 received 3 mg/kg on days 1-4 and...
متن کاملVisceral Leishmaniasis Treatment, Italy
First-line drug treatment was recorded in 573 immunocompetent patients with visceral leishmaniasis in Italy. In the past 12 years, the proportion of antimonial treatments decreased from 100% to 2.8%, while the proportion of amphotericin B treatments increased from 0% to 97.2%. The countrywide change in therapy is a response to both disease reemergence and increasing antimonial failure.
متن کاملTreatment of visceral leishmaniasis.
I agree with the authors statement, “It is an important alternative especially in patient who did not respond to conventional pentavalent antimony therapy given alone or in combination with other agents”. But they stated their experience with L-AmB treatment without trying conventional treatment. Therefore I am not in agreement with their belief that “this drug may be the first choice of treatm...
متن کاملTreatment of Mediterranean visceral leishmaniasis.
Up-to-date information is given on the epidemiological situation of zoonotic visceral leishmaniasis (ZVL) in nine Mediterranean countries, and on drug regimens adopted in the management of ZVL patients in each country. Results of experimental and clinical trials on the efficacy and tolerability of liposomal amphotericin B in laboratory animals and in patients with ZVL are presented, as well as ...
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ژورنال
عنوان ژورنال: Archives of Disease in Childhood
سال: 1995
ISSN: 0003-9888,1468-2044
DOI: 10.1136/adc.73.2.157